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Lynn Chiu
KLI Colloquia
Life Enabled: A General Principle of Biological Identity
2017-10-06 15:00 - 2017-10-06 16:30
Organized by KLI

Topic description:

In almost all domains of the life sciences, major historical debates are dominated by a division between internalists vs. externalists schools of thought (Gould 1977, Wilson 2004, 2005, Godfrey-Smith 1996, Bechtel and Richardson 1993/2010). Internalists and externalists have argued over nature (genetics) vs. nurture (culture), the content and vehicles of mental states, the causes of biological forms and function, the sources of adaptive evolution, the specification of immune self-recognition, the development of language, etc.

In this talk, I sketch out the basis of a future research proposal. The goal is to identify and characterize a general principle in biology and show how it can reconcile the internal vs. external dichotomy. The principle is that living systems, through their activities, explorations, and modes of interactions (“enabling causes”), tend to actively create the internal and external conditions that in turn enable “constitutive causes” to come together and give rise to biological form, function, and relative fitness.

The project will consist of two parts. First, I will focus on historical episodes in immunology and cancer biology, where internalist vs. externalist camps have argued over the ultimate cause of cellular identity. I will seek out “middle-ground” positions that have been sidelined or mischaracterized as merely interactive or purely internal/external, but in fact provide what I call “enabling causes” that defy the internal vs. external distinction. I then lay out how to test the generality of this “enabling” principle of biology and draw out its consequences for debates about biological identity.


Biographical note:

I am a philosopher of science specializing in philosophy of biology (eco-evo-devo, immunology), cognition, and perception. In 2015, I received my Ph.D. in Philosophy from University of Missouri under the supervision of André Ariew. Since 2015, I’ve been working as a CNRS postdoc in the ImmunoConcept Lab at University of Bordeaux, under Thomas Pradeu’s ERC Starting Grant “Immunity, DEvelopment and the Microbiota (IDEM): Understanding the Continuous Construction of Biological Identity.”